The sentinel lymph node biopsy (SLNB) has become established as the gold standard for clinically node-negative patients with primary mammary carcinomas. To exploit the benefits of this procedure, the sentinel lymph nodes are often analysed intra-operatively. The investigation is often made using frozen section or imprint cytology with subsequent HE stain (haematoxylin-eosin). These histopathological methods, however, have limited sensitivity, as only a small section of the lymph node tissue can be investigated during surgery. In contrast, the OSNA^® system allows the intraoperative analysis of the entire lymph node, thereby allowing a more accurate assessment of the extent of the metastatic spread. An earlier definitive decision on the necessary therapeutic measures can then be made during the surgical procedure.

•    The entire lymph node can be analysed
•    Intraoperative decision, immediate and reliable
•    Clear indication of the axillary status
•    Second operations can be avoided
•    Immediate reconstructions possible
•    Prompt initiation of further therapeutic measures
•    Shorter waiting time and less stress for the patient